Cholyl-lys-fluorescein
WebCholyl-l-lysyl-fluorescein (CLF) is a fluorescent bile salt derivative that is being developed as an agent for determining in vivo liver function. However, the mechanisms of uptake and excretion by hepatocytes have not been rigorously studied. We have … WebChromatography and Mass Spectrometry. Avantor has the resources to make your Chromatography or Mass Spectrometry applications run efficiently and effectively—from the measuring apparatus needed for chromatography, or the proteins used to fulfill sample …
Cholyl-lys-fluorescein
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WebPlasma elimination of cholyl-lysyl-fluorescein (CLF): a pilot study in patients with liver cirrhosisAuthors: Milkiewicz P, Saksena S, Cardenas T, Mills CO, Elias E.Journal: Liver (2000): 330 Hepatocyte coupletsAuthors: Coleman R, Roma MG. Journal: Biochem Soc Trans (2000): 136 WebMay 22, 2015 · Cholyl-lysyl-fluorescein (CLF) is a fluorescein-labelled bile acid whose biological behaviour closely resembles that of naturally occurring cholyl glycine. The aim of this study was to...
WebCholyl-lys-fluorescein (CLF/cholyl-lys-F) is a bile acid (BA) analog, developed to investigate and determine in vivo liver functions. The compound is actually a fluorescein-labeled bile acid derivative with similar properties to the naturally occurring … WebFeb 1, 2024 · The fluorescent bile acid-derivative cholyl-l-lysyl-fluorescein (CLF) was used to quantify drug-induced efflux transport inhibition in hepatocytes. Cyclosporine inhibited CLF accumulation in the apical bile canalicular lumen in a concentration-dependent manner.
WebCLF is a fluorescein-labeled bile acid analog that closely parallels the cellular binding and uptake properties of cholic acid derivatives. It is a divalent 'unipolar' anionic fluorescent monohydroxy bile salt analog with physical, biological and cholestatic properties that are … Web(3) Fluorescein isothiocyanate (FITC)-ricin exhibited binding to schistosomula and adult worms, but not to cercariae or to freshly transformed schistosomula. (4) The greater biliary excretion and hepatic extraction of cholyl-lys-F relative to free fluorescein further suggest that conjugation with a bile salt may be an efficient way of targeting ...
WebCLF是荧光素标记的胆汁酸类似物,与胆酸衍生物的细胞结合和吸收特性密切相关。 它是一种二价的“单极性”阴离子荧光单羟基胆盐类似物,具有与石胆酸类似的物理、生物和胆汁抑制特性,肝胆酸及其衍生物为研究单羟基胆盐致肝细胞胆汁淤积的机制提供了一个有用的途径。 CLF目前被用作肝组织内胆汁酸转运的工具。 百萤生物是 AAT Bioquest 的中国代理 …
WebCLF is mainly secreted into bile canaliculi by Bile Salt Efflux Pump (BSEP).Corning® Gentest™ CLF is suitable for studying the inhibition of bile acid efflux transporters, which is one mechanism involved in drug-induced cholestasis. tracy longworth architecthttp://junyiyantj.gongyingshi.com/item/show/23643765 tracy lord citrus countyWebCLF是荧光素标记的胆汁酸类似物,与胆酸衍生物的细胞结合和吸收特性密切相关。 它是一种二价的“单极性”阴离子荧光单羟基胆盐类似物,具有与石胆酸类似的物理、生物和胆汁抑制特性,肝胆酸及其衍生物为研究单羟基胆盐致肝细胞胆汁淤积的机制提供了一个有用的 … tracy lorenz suffolk county clerkWebCholyl-lysyl-fluorescein was kindly provided by Dr. Charles O. Mills (Birmingham, UK) and its purity was confirmed according to the methods of Mills et al. (1991); cyclosporin A (Sandoz Pharma... tracy lorraine ebook hunterWebDec 6, 1991 · Cholyl-lys-F was synthesized employing equimolar amounts of cholyl-lys (sodium salt) and fluorescein isothiocyanate (FITC) in bicarbonate buffer (pH 9.5) over 16 h at room temperature (21 degrees C) with a yield of 70%. The fluorescent property of … the royal school ghanaWebDec 6, 1991 · Cholyl-lys-F was synthesized employing equimolar amounts of cholyl-lys (sodium salt) and fluorescein isothiocyanate (FITC) in bicarbonate buffer (pH 9.5) over 16 h at room temperature (21°C) with a yield of 70%. The fluorescent property of cholyl-lys-F … tracy lord wedding dressWebCLF [Cholyl-Lys-Fluorescein] 市场价 ¥3,540.00 好评率 100% (0)条评论 商城价 登录后可查看价格 tracy lothian